Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Cysteine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.67 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.40 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL12505856 | 1.00 | PTGS1 (0.67) | PTGS1SLC7A11SLC7A5ENPEPGLRA1 | |
| Serine SCHEMBL15417923 | 0.93 | PTGS1 (0.57) | PTGS1SLC7A11SLC7A5ENPEPGLRA1 | |
| Cysteine SCHEMBL14485654 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A3 | |
| Cysteine SCHEMBL1675940 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A3 | |
| Cysteine SCHEMBL523189 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A3 | |
| Cysteine SCHEMBL1675939 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPSLC1A3 | |
| Cysteine SCHEMBL3320713 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPGLRA1 | |
| Cysteine SCHEMBL3320717 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPGLRA1 | |
| Cysteine SCHEMBL6028716 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPGLRA1 | |
| Cysteine SCHEMBL1268415 | 0.91 | PTGS1 (0.80) | PTGS1SLC7A11SLC7A5ENPEPGLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054578-A1 | Elastin peptide analogs and uses thereof | SANDBERG LAWRENCE B (US) | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054578-A1 | Elastin peptide analogs and uses thereof | ELANE, CUTA, ENPEP | PTGS1 1903/4885SLC7A11 3769/4885SLC7A5 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.