Cysteine

Cysteine

SCHEMBL1268415

NC(CS)C(=O)O.NCC(=O)O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Cysteine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.80
SLC7A11 Q9UPY5 1/20 0.80
GLRA1 P23415 1/20 0.50
SLC6A9 P48067 1/20 0.50
OR51E2 Q9H255 1/20 0.50
GSR P00390 2/20 0.46
GRIK1 P39086 2/20 0.46
GRIK2 Q13002 2/20 0.46
GRM1 Q13255 2/20 0.46
GRM2 Q14416 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
SLC1A3 P43003 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cysteine SCHEMBL902046 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL3320713 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL6675043 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL2233580 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL3320717 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL6028716 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL1907826 1.00 PTGS1 (0.80) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Cysteine SCHEMBL28436580 0.98 PTGS1 (0.76) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Aspartic Acid SCHEMBL8628354 0.91 PTGS1 (0.67) PTGS1SLC7A11GLRA1SLC6A9OR51E2
Serine SCHEMBL418635 0.91 PTGS1 (0.67) PTGS1SLC7A11GLRA1SLC6A9OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117405800-A Method for simultaneously detecting reduced biological ammonia sulfhydryl compound and oxidized biological ammonia sulfhydryl compound 上海中医药大学 2024-01-16 CN claimed
CN-106906198-A Cellulase for improving temperature resistance 东莞泛亚太生物科技有限公司 2017-06-30 CN claimed
CN-104172194-A FOOD COMPOSITION FOR BINDING ACETALDEHYDE IN MOUTH AND IN DIGESTIVE TRACK, AND METHOD FOR THE PREPARATION OF THE COMPOSITION BIOHIT OY J 2014-12-03 CN claimed
US-8758812-B2 Composition for foodstuff for binding acetaldehyde BIOHIT OYJ (FI) 2014-06-24 US claimed
WO-2013001167-A1 NON-TOXIC COMPOSITIONS FOR DECREASING THE RISK OF CANCER CAUSED BY ORAL MICROBES BIOHIT OYJ (FI) 2013-01-03 WO claimed
US-8227513-B2 Food composition for binding acetaldehyde in mouth and in digestive track, and method for the preparation of the composition BIOHIT OYJ (FI) 2012-07-24 US claimed
US-20110171296-A1 METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, THE STOMACH AND THE LARGE INTESTINE BIOHIT OYJ (FI) 2011-07-14 US claimed
US-20100239663-A1 COMPOSITION FOR FOODSTUFF FOR BINDING ACETALDEHYDE BIOHIT OYJ (FI) 2010-09-23 US claimed
US-20100063149-A1 FOOD COMPOSITION FOR BINDING ACETALDEHYDE IN MOUTH AND IN DIGESTIVE TRACK, AND METHOD FOR THE PREPARATION OF THE COMPOSITION BIOHIT OYJ (FI) 2010-03-11 US claimed
CN-101668522-A Composition and method for binding acetaldehyde in stomach BIOHIT OYJ 2010-03-10 CN claimed
WO-2007135242-A1 COMPOSITION FOR FOODSTUFF FOR BINDING ACETALDEHYDE BIOHIT OYJ (FI) 2007-11-29 WO claimed
WO-2007135241-A2 COMPOSITION AND METHOD FOR BINDING ACETALDEHYDE IN STOMACH BIOHIT OYJ (FI) 2007-11-29 WO claimed
US-20070148215-A1 Therapeutically active dressings, their manufacture and use SANGUIBIOTECH GMBH (DE) 2007-06-28 US claimed
WO-2006103316-A1 FOOD COMPOSITION FOR BINDING ACETALDEHYDE IN MOUTH AND IN DIGESTIVE TRACK, AND METHOD FOR THE PREPARATION OF THE COMPOSITION BIOHIT OYJ (FI) 2006-10-05 WO claimed
WO-2006037848-A1 METHOD AND PREPARATION FOR BINDING ALDEHYDES IN SALIVA BIOHIT OYJ (FI) 2006-04-13 WO claimed
US-20050267042-A1 Method and preparation for binding acetaldehyde in saliva, stomach and large intestine BIOHIT OYJ (FI) 2005-12-01 US claimed
CN-1486177-A Method and formulation for binding acetaldehyde in saliva, stomach and large intestine ϣ�������ع����޹�˾ 2004-03-31 CN claimed
EP-1339394-A1 METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, STOMACH AND LARGE INTESTINE BIOHIT OYJ (FI) 2003-09-03 EP claimed
WO-2002036098-A1 METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, STOMACH AND LARGE INTESTINE LICENTIA LTD (FI) 2002-05-10 WO claimed
WO-2002005785-A1 MODULATED RELEASE THERAPEUTIC AEROSOLS AEROPHARM TECHNOLOGY INCORPORATED (US) 2002-01-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239663-A1 COMPOSITION FOR FOODSTUFF FOR BINDING ACETALDEHYDE FABP2, ALDH16A1, ALDH1A1 PTGS1 599/4885SLC7A11 84/4885GLRA1 712/4885
US-20050267042-A1 Method and preparation for binding acetaldehyde in saliva, stomach and large intestine SI, ADH1A, ADH1C PTGS1 1219/4885SLC7A11 738/4885GLRA1 931/4885
US-20100063149-A1 FOOD COMPOSITION FOR BINDING ACETALDEHYDE IN MOUTH AND IN DIGESTIVE TRACK, AND METHOD FOR THE PREPARATION OF THE COMPOSITION FABP2, FABP6, ADH1A PTGS1 1736/4885SLC7A11 1527/4885GLRA1 2405/4885
US-20110171296-A1 METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, THE STOMACH AND THE LARGE INTESTINE SI, ADH1C, ADH1A PTGS1 764/4885SLC7A11 1651/4885GLRA1 1306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.