Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 15/20 | 0.59 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510240 | 0.90 | ITGB1 (0.48) | ITGA4ITGB1ITGB7HTTMEN1 | |
| SCHEMBL7610354 | 0.85 | ITGB1 (0.63) | ITGA4ITGB1ITGB7HTTITGA2 | |
| SCHEMBL6560946 | 0.79 | MAPT (0.49) | ITGA4ITGB1ITGB7HTTMEN1 | |
| SCHEMBL6560411 | 0.78 | ITGA4 (0.51) | ITGA4ITGB1ITGB7HTTALDH1A1 | |
| SCHEMBL6560407 | 0.78 | ITGA4 (0.51) | ITGA4ITGB1ITGB7HTTALDH1A1 | |
| SCHEMBL6561753 | 0.78 | ITGA4 (0.51) | ITGA4ITGB1ITGB7HTTALDH1A1 | |
| SCHEMBL7516096 | 0.77 | ITGA4 (0.49) | ITGA4ITGB1ITGB7MEN1KMT2A | |
| SCHEMBL7098193 | 0.77 | ITGA4 (0.49) | ITGA4ITGB1ITGB7MEN1KMT2A | |
| SCHEMBL7098189 | 0.77 | ITGA4 (0.49) | ITGA4ITGB1ITGB7MEN1KMT2A | |
| SCHEMBL7264082 | 0.76 | ITGB1 (0.68) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911451-B1 | Phenylalanine derivatives | CELLTECH R&D LIMITED (GB) | 2005-06-28 | — | — | US | disclosed |