Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516319 | 0.90 | ITGA4 (0.59) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6560946 | 0.89 | MAPT (0.49) | ITGB1ITGA4HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6563404 | 0.81 | HTT (0.55) | ITGB1ITGA4HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6563409 | 0.81 | HTT (0.55) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL7485965 | 0.80 | TSHR (0.55) | ITGB1ITGA4KMT2AITGB7TSHR | |
| SCHEMBL6561143 | 0.79 | HTT (0.43) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6561140 | 0.79 | HTT (0.43) | ITGB1ITGA4HTTMEN1KMT2A | |
| SCHEMBL6519624 | 0.79 | ITGB1 (0.63) | ITGB1ITGA4 | |
| SCHEMBL28883406 | 0.76 | NOS2 (0.55) | MEN1KMT2AALDH1A1ATMPOLB | |
| SCHEMBL7610354 | 0.76 | ITGB1 (0.63) | ITGB1ITGA4HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911451-B1 | Phenylalanine derivatives | CELLTECH R&D LIMITED (GB) | 2005-06-28 | — | — | US | disclosed |