Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511749 | 0.91 | HTT (0.38) | BCL2L1BAK1HTTKDM4ELMNA | |
| SCHEMBL6532106 | 0.89 | BCL2L1 (0.42) | BCL2L1BAK1HTTKDM4ELMNA | |
| SCHEMBL6512708 | 0.85 | HTT (0.45) | BCL2L1BAK1HTTKDM4ELMNA | |
| SCHEMBL6512680 | 0.85 | FFAR1 (0.44) | MEN1KMT2A | |
| SCHEMBL6515374 | 0.81 | ALDH1A1 (0.41) | CA12CA1CA2CA4ALDH1A1 | |
| SCHEMBL6527447 | 0.80 | S1PR1 (0.43) | ALDH1A1 | |
| SCHEMBL6511703 | 0.79 | NPC1 (0.40) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL6533434 | 0.78 | BCL2L1 (0.37) | BCL2L1BAK1HTTKDM4EMEN1 | |
| SCHEMBL6511147 | 0.78 | TSHR (0.47) | — | |
| SCHEMBL6508922 | 0.78 | ATM (0.35) | BCL2L1BAK1HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |