Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527447 | 0.97 | S1PR1 (0.43) | ALDH1A1S1PR1S1PR3S1PR2THRA | |
| SCHEMBL6507818 | 0.89 | KDM4E (0.38) | S1PR1 | |
| SCHEMBL6511871 | 0.86 | PPARA (0.39) | S1PR1S1PR3S1PR2THRATHRB | |
| SCHEMBL6516568 | 0.86 | PPARA (0.41) | S1PR1S1PR3S1PR2THRATHRB | |
| SCHEMBL6516489 | 0.81 | BCL2L1 (0.39) | ALDH1A1HPGDCA12CA1CA2 | |
| SCHEMBL6512680 | 0.81 | FFAR1 (0.44) | — | |
| SCHEMBL6511970 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10S1PR1S1PR3 | |
| SCHEMBL6515031 | 0.80 | MEP1B (0.43) | — | |
| SCHEMBL6533434 | 0.79 | BCL2L1 (0.37) | ALDH1A1THRB | |
| SCHEMBL6532417 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |