Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516489 | 0.85 | BCL2L1 (0.39) | HTTLMNAPKMMEN1MAPT | |
| SCHEMBL6511912 | 0.84 | HTT (0.45) | HTTLMNAPKMFFAR4MEN1 | |
| SCHEMBL6511915 | 0.84 | HTT (0.45) | HTTLMNAPKMFFAR4MEN1 | |
| SCHEMBL6532106 | 0.84 | BCL2L1 (0.42) | HTTLMNAPKMMEN1MAPT | |
| SCHEMBL6515095 | 0.83 | FFAR1 (0.45) | HTTPKMMEN1KMT2AMEP1B | |
| SCHEMBL6511703 | 0.81 | NPC1 (0.40) | FFAR4MEN1MAPTKMT2AMEP1B | |
| SCHEMBL6511749 | 0.81 | HTT (0.38) | HTTLMNAPKMFFAR4MEN1 | |
| SCHEMBL6509442 | 0.80 | RAB9A (0.41) | HTTLMNAPKMFFAR4MEP1B | |
| SCHEMBL6510665 | 0.77 | MEP1B (0.39) | HTTLMNAMAPTKMT2AMEP1B | |
| SCHEMBL6510768 | 0.77 | ALDH1A1 (0.43) | HTTLMNAFFAR4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |