Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509314 | 0.91 | MEP1B (0.46) | CYP2D6MEP1BHPGDPLA2G4BKCNH2 | |
| SCHEMBL6515110 | 0.89 | HPGD (0.47) | CYP2D6MEP1BHPGDKDM4EMAPK1 | |
| SCHEMBL6511186 | 0.85 | HDAC3 (0.46) | CYP2D6MEP1BPLA2G4BPPARGPPARA | |
| SCHEMBL6515073 | 0.85 | PLA2G4B (0.47) | CYP2D6MEP1BPLA2G4BKCNH2NR1H3 | |
| SCHEMBL6512685 | 0.84 | FFAR1 (0.43) | MEP1BHPGDFFAR1 | |
| SCHEMBL6511831 | 0.84 | FFAR1 (0.57) | MEP1BFFAR1PPARGPPARA | |
| SCHEMBL6511846 | 0.84 | FFAR1 (0.44) | MEP1BHPGDKDM4EMAPK1FFAR1 | |
| SCHEMBL6508452 | 0.83 | NPC1 (0.44) | LTB4RLTB4R2PPARGPPARA | |
| SCHEMBL6515065 | 0.83 | TSHR (0.55) | FFAR1PPARGPPARA | |
| SCHEMBL6515031 | 0.83 | MEP1B (0.43) | CYP2D6MEP1BPLA2G4BLTB4R2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |