Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516580 | 0.89 | CYP2D6 (0.50) | HPGDPPARGPPARAMEP1BKDM4E | |
| SCHEMBL6515065 | 0.83 | TSHR (0.55) | PPARGPPARAFFAR1 | |
| SCHEMBL6509563 | 0.83 | CALM1 (0.51) | HPGDMEP1BKDM4EALDH1A1FFAR1 | |
| SCHEMBL6512685 | 0.82 | FFAR1 (0.43) | HPGDMEP1BFFAR1MEN1KMT2A | |
| SCHEMBL6509273 | 0.82 | MEP1B (0.53) | MEP1BKDM4ENR1H3ALDH1A1FFAR1 | |
| SCHEMBL6511831 | 0.81 | FFAR1 (0.57) | PPARGPPARAMEP1BFFAR1 | |
| SCHEMBL6511846 | 0.81 | FFAR1 (0.44) | HPGDMEP1BKDM4EMAPK1FFAR1 | |
| SCHEMBL6509243 | 0.81 | SLC2A1 (0.48) | PPARGPPARAALDH1A1FFAR1MEN1 | |
| SCHEMBL6508226 | 0.81 | CETP (0.52) | MEP1BFFAR1 | |
| SCHEMBL6515378 | 0.80 | FFAR1 (0.52) | PPARGPPARAMEP1BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |