SCHEMBL6517017

SCHEMBL6517017

CCCCCC[Si](O)([SiH3])CCCCCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX1 P07099 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
DNM1 Q05193 4/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1493941 0.97 TSHR (0.39) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL3482912 0.88 TSHR (0.35) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL3239743 0.85 LMNA (0.35) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL3481811 0.83 ALDH1A1 (0.32) TSHRTHRBLMNAALDH1A1SMN1; SMN2
SCHEMBL3482112 0.78
SCHEMBL1687021 0.77 TSHR (0.50) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL2922266 0.77 TSHR (0.50) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL2917797 0.77 TSHR (0.50) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL17090784 0.77 TSHR (0.50) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL10984369 0.77 TSHR (0.50) TSHRTHRBLMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050257558-A1 Heat exchanger for air and freezer device DAIKIN INDUSTRIES, LTD. (JP) 2005-11-24 US disclosed
EP-1580514-A1 HEAT EXCHANGER FOR AIR AND FREEZER DEVICE Daikin Industries, Ltd. (JP) 2005-09-28 EP disclosed
US-5786435-A COATINGS; WATER RESISTANCE, CHEMICAL RESISTANCE, WEAR RESISTANCE MAZDA MOTOR CORPORATION (JP) 1998-07-28 US disclosed
EP-0358238-B1 Resin compositions and a method of curing the same KANSAI PAINT CO LTD (JP) 1996-06-05 EP disclosed
US-5492968-A CONTAINS A HIGH MOLECULAR WEIGHT COMPOUND CONTAINING HYDROXY AND EPOXY GROUPS, A SILANE COMPOUND AND A METAL CHELATE COMPOUND KANSAI PAINT COMPANY LIMITED (JP) 1996-02-20 US disclosed
EP-0687712-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-12-20 EP disclosed
EP-0682086-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-15 EP disclosed
EP-0681003-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-08 EP disclosed
US-5418293-A Fluoropolymer, epoxy or silicone compound KANSAI PAINT COMPANY, LIMITED (JP) 1995-05-23 US disclosed
US-5389727-A Low temperature curing, weatherproofing KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-14 US disclosed
US-5387646-A Protective coating; blend of an organosilicon and epoxy polymer KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-07 US disclosed
US-5284919-A Low temperature curing, waterproofing, acid resistance KANSAI PAINT COMPANY, LIMITED (JP) 1994-02-08 US disclosed
US-5026793-A Containing hydroxy, epoxy, and silane compounds with chelate compound containing aluminum, titanium, or zironium KANSAI PAINT COMPANY LIMITED (JP) 1991-06-25 US disclosed
EP-0358238-A2 Resin compositions and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP disclosed