Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517017 | 0.97 | TSHR (0.44) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3482912 | 0.91 | TSHR (0.35) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3481811 | 0.86 | ALDH1A1 (0.32) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3239743 | 0.82 | LMNA (0.35) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| SCHEMBL3482112 | 0.80 | — | — | |
| SCHEMBL3482575 | 0.78 | — | — | |
| SCHEMBL838158 | 0.75 | TSHR (0.44) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL618894 | 0.75 | TSHR (0.44) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL403359 | 0.75 | — | — | |
| SCHEMBL562896 | 0.74 | TSHR (0.50) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470574-B1 | PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION | BRIDGESTONE CORP (JP) | 2014-09-17 | — | — | EP | disclosed |
| US-8765887-B2 | Process and catalyst system for polydiene production | BRIDGESTONE CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-2470574-A2 | PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION | Bridgestone Corporation (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-20120165484-A1 | PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION | BRIDGESTONE CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| WO-2011028523-A2 | PROCESS AND CATALYST SYSTEM FOR POLYDIENE PRODUCTION | BRIDGESTONE CORPORATION (JP) | 2011-03-10 | — | — | WO | disclosed |