Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517209 | 1.00 | NPC1 (0.33) | NPC1RAB9AMAPTSMN1; SMN2FUCA1 | |
| SCHEMBL7259419 | 0.88 | NPC1 (0.35) | NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7259421 | 0.88 | NPC1 (0.35) | NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6048091 | 0.81 | — | — | |
| SCHEMBL6520738 | 0.80 | FUCA1 (0.31) | FUCA1 | |
| SCHEMBL6520744 | 0.80 | FUCA1 (0.31) | FUCA1 | |
| SCHEMBL6048093 | 0.77 | — | — | |
| SCHEMBL6515145 | 0.76 | DNM1 (0.35) | FUCA1 | |
| SCHEMBL6515149 | 0.76 | DNM1 (0.35) | FUCA1 | |
| SCHEMBL6370657 | 0.76 | NPC1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272670-A1 | Synthesis and use of glycodendrimer reagents | DAVIS BENJAMIN G | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272670-A1 | Synthesis and use of glycodendrimer reagents | STT3A, PTMS, STT3B | NPC1 1037/4885RAB9A 3035/4885MAPT 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.