SCHEMBL6520744

SCHEMBL6520744

NCCN(CCNC(=O)C[C@H]1S[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O)CCNC(=O)C[C@H]1S[C@@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520738 1.00 FUCA1 (0.31) FUCA1
SCHEMBL5575978 0.85 FUCA1 (0.32) FUCA1
SCHEMBL5575973 0.85 FUCA1 (0.32) FUCA1
SCHEMBL6515149 0.81 DNM1 (0.35) FUCA1
SCHEMBL6515145 0.81 DNM1 (0.35) FUCA1
SCHEMBL6517209 0.80 NPC1 (0.33) FUCA1
SCHEMBL6517205 0.80 NPC1 (0.33) FUCA1
SCHEMBL5575339 0.78 FUCA1 (0.33) FUCA1
SCHEMBL5575333 0.78 FUCA1 (0.33) FUCA1
Hydrogen Sulfide SCHEMBL4468953 0.77 PYGB (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050272670-A1 Synthesis and use of glycodendrimer reagents DAVIS BENJAMIN G 2005-12-08 US disclosed
US-6627744-B2 A chemically modified mutant protein, e.g. an enzyme, having a substituted cysteine reacted with a glyosyslated thiosulfate; high esterase activity and low amidase activity of subtilisins; protease to degrade lectins GENENCOR INTERNATIONAL, INC. 2003-09-30 US disclosed
US-20020019039-A1 Synthesis and use of glycodendrimer reagents GENENCOR INTERNATIONAL, INC. 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019039-A1 Synthesis and use of glycodendrimer reagents STT3A, STT3B, PTMS FUCA1 408/4885
US-20050272670-A1 Synthesis and use of glycodendrimer reagents STT3A, PTMS, STT3B FUCA1 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.