SCHEMBL6518877

SCHEMBL6518877

Cc1ccc(C=C(C(=O)O)C(CC(=O)Oc2ccc(C)cc2)C(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 5/20 0.39
L3MBTL1 Q9Y468 2/20 0.36
NPC1 O15118 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PPARA Q07869 1/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HPGD P15428 1/20 0.35
AKR1C3 P42330 1/20 0.35
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6523112 0.95 ALDH1A1 (0.43) LMNAGAAALDH1A1KMT2ANPC1
SCHEMBL6520854 0.95 ALDH1A1 (0.40) LMNAGAAALDH1A1KMT2ANPC1
SCHEMBL6524372 0.86 APP (0.36) LMNAALDH1A1KMT2ATDP1MEN1
SCHEMBL6517374 0.85 CYP19A1 (0.38) ALDH1A1KMT2APPARAMEN1AKR1C3
SCHEMBL6518811 0.81 AKR1C3 (0.38) LMNAALDH1A1KMT2ANPC1MAPT
SCHEMBL6514780 0.81 ALDH1A1 (0.40) LMNAGAAALDH1A1KMT2AL3MBTL1
SCHEMBL6524257 0.81 KMT2A (0.36) LMNAALDH1A1KMT2AL3MBTL1TDP1
SCHEMBL6516689 0.80 KDM4E (0.43) GAAALDH1A1KMT2AL3MBTL1TDP1
SCHEMBL6514389 0.80 LMNA (0.45) LMNAALDH1A1KMT2AL3MBTL1MEN1
SCHEMBL6515897 0.79 MAPT (0.48) LMNAALDH1A1KMT2AL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed