SCHEMBL6516689

SCHEMBL6516689

Cc1ccc(OC(=O)CC(C(=O)O)C(=Cc2cccc3ccccc23)C(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SIRT5 Q9NXA8 1/20 0.39
SMPD2 O60906 2/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 2/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
PPARG P37231 3/20 0.35
PPARA Q07869 3/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
CRHBP P24387 1/20 0.35
HTT P42858 1/20 0.35
CRHR2 Q13324 1/20 0.35
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520284 0.92 KDM4E (0.44) KDM4ETDP1L3MBTL1SIRT5SMPD2
SCHEMBL6520790 0.83 KDM4E (0.45) KDM4EL3MBTL1SMPD2ALDH1A1MAPT
SCHEMBL6523112 0.83 ALDH1A1 (0.43) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL6514780 0.81 ALDH1A1 (0.40) KDM4ETDP1L3MBTL1ALDH1A1MAPT
SCHEMBL6520854 0.80 ALDH1A1 (0.40) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL6518877 0.80 LMNA (0.40) KDM4ETDP1L3MBTL1ALDH1A1MAPT
SCHEMBL6516609 0.78 KDM4E (0.49) KDM4ESMPD2ALDH1A1MAPTMEN1
SCHEMBL6518901 0.77 KDM4E (0.41) KDM4ETDP1SMPD2ALDH1A1MAPT
SCHEMBL6518068 0.77 KDM4E (0.41) KDM4ETDP1SMPD2ALDH1A1MAPT
SCHEMBL6524361 0.77 KDM4E (0.47) KDM4ESMPD2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 KDM4E 329/4885TDP1 1789/4885L3MBTL1 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.