Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646610 | 0.91 | GPR35 (0.48) | GPR35TSHRCYP3A4KDM4EGRIN2D | |
| SCHEMBL11683811 | 0.83 | GPR35 (0.57) | GPR35TSHRCYP3A4KDM4EGRIN2D | |
| SCHEMBL4443083 | 0.82 | GPR35 (0.48) | GPR35TSHRCYP3A4KDM4EALDH1A1 | |
| SCHEMBL6535736 | 0.80 | GPR35 (0.59) | GPR35TSHRCYP3A4KDM4EGRIN2D | |
| Hydrochloric Acid SCHEMBL27560354 | 0.78 | GPR35 (0.57) | GPR35TSHRCYP3A4KDM4EGRIN2D | |
| SCHEMBL3814710 | 0.78 | KIF18A (0.39) | TSHRALDH1A1TDP1MAPTCYP1A2 | |
| SCHEMBL137704 | 0.76 | TSHR (0.58) | GPR35TSHRCYP3A4TDP1VCAM1 | |
| SCHEMBL28522129 | 0.76 | GPR35 (0.48) | GPR35TSHRCYP3A4KDM4EGRIN2D | |
| SCHEMBL27820860 | 0.75 | GPR35 (0.49) | GPR35TSHRCYP3A4KDM4EGRIN2D | |
| SCHEMBL28776957 | 0.75 | TDP1 (0.52) | GPR35TSHRALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |