SCHEMBL28522129

SCHEMBL28522129

Cc1cc([N+](=O)[O-])c(S(=O)(=O)NN)c([N+](=O)[O-])c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.48
TSHR P16473 4/20 0.44
CYP3A4 P08684 3/20 0.44
ALDH1A1 P00352 7/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 2/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
VCAM1 P19320 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273384 0.80 ALDH1A1 (0.50) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
SCHEMBL11683811 0.79 GPR35 (0.57) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
SCHEMBL12190333 0.76 CA1 (0.49) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
SCHEMBL6518952 0.76 GPR35 (0.53) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
SCHEMBL6535736 0.76 GPR35 (0.59) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
SCHEMBL12098068 0.75 ALDH1A1 (0.46) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL27560354 0.74 GPR35 (0.57) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL15619260 0.74 ALDH1A1 (0.44) GPR35TSHRCYP3A4ALDH1A1L3MBTL1
SCHEMBL422151 0.72 CA1 (0.63) TSHRCYP3A4ALDH1A1L3MBTL1MAPT
SCHEMBL11802737 0.72 GPR35 (0.64) GPR35TSHRCYP3A4ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109305983-B Synthesis method of cyclopropylboronic acid 沧州普瑞东方科技有限公司 2021-01-05 CN disclosed