Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | STAT5B | P51692 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510616 | 0.82 | CTSK (0.32) | BCHEACHE | |
| SCHEMBL7986714 | 0.81 | HDAC1 (0.41) | CA1CA2CA12STAT5BL3MBTL1 | |
| SCHEMBL7972044 | 0.81 | HDAC1 (0.41) | CA1CA2CA12STAT5BL3MBTL1 | |
| SCHEMBL6519214 | 0.81 | METAP2 (0.39) | METAP2TRPV4PDK2BCHEACHE | |
| SCHEMBL29059938 | 0.81 | METAP2 (0.35) | METAP2TRPV4PDK2F2GLS | |
| SCHEMBL3244228 | 0.79 | CA1 (0.54) | CA1CA2CA12CA9NQO2 | |
| SCHEMBL2587707 | 0.79 | CA1 (0.54) | CA1CA2CA12CA9NQO2 | |
| SCHEMBL644416 | 0.76 | CA12 (0.40) | CA2CA12CA9 | |
| SCHEMBL6130696 | 0.76 | CA12 (0.32) | CA1CA2CA12CA9L3MBTL1 | |
| SCHEMBL10598218 | 0.75 | SNCA (0.39) | CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908903-B1 | Cluster clearing agents | ALETHEON PHARMACEUTICALS, INC. (US) | 2005-06-21 | — | — | US | disclosed |
| US-6172045-B1 | COMPLEX CONTAINING 1-DESOXY-1-THIO-N-ACETYLGALACTOSAMINE | NEORX CORPORATION | 2001-01-09 | — | — | US | disclosed |
| WO-1997046098-A9 | CLUSTER CLEARING AGENTS | — | 1998-08-06 | — | — | WO | disclosed |