Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | STAT5B | P51692 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972044 | 1.00 | HDAC1 (0.41) | HDAC1HDAC3HDAC2NCOR2CRHBP | |
| SCHEMBL7972042 | 0.84 | HDAC1 (0.42) | HDAC1HDAC3HDAC2NCOR2STAT5B | |
| SCHEMBL6519209 | 0.81 | METAP2 (0.37) | STAT5BL3MBTL1CA12CA1CA2 | |
| SCHEMBL16684875 | 0.79 | KMT2A (0.44) | CRHBPCRHR2L3MBTL1LTB4RKMT2A | |
| SCHEMBL8525848 | 0.79 | HDAC3 (0.56) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL6130696 | 0.77 | CA12 (0.32) | L3MBTL1CA12CA1CA2 | |
| SCHEMBL8021840 | 0.77 | HDAC3 (0.55) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8021179 | 0.77 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8240094 | 0.77 | S1PR3 (0.40) | HDAC1HDAC3HDAC2NCOR2STAT5B | |
| SCHEMBL7973240 | 0.75 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |