SCHEMBL6519628

SCHEMBL6519628

Fc1cc(F)c(-c2c(F)c(-c3c(F)cc(F)cc3F)c(F)c(-c3c(F)cc(F)cc3F)c2F)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.40
CES1 P23141 3/20 0.40
TGM2 P21980 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
ERN1 O75460 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12578957 0.89 CES2 (0.39) CES2CES1TGM2ALDH1A1CA12
SCHEMBL17515030 0.75 TGM2 (0.32) CES2CES1TGM2ALDH1A1CA12
SCHEMBL17514549 0.75 RAPGEF4 (0.48) CES2CES1TGM2ALDH1A1RAPGEF4
SCHEMBL531337 0.74 CES2 (0.52) CES2CES1TGM2ALDH1A1CA12
SCHEMBL12693559 0.73 CA1 (0.31) CA12CA1
SCHEMBL17514468 0.73 TGM2 (0.31) CES2CES1TGM2
SCHEMBL14926556 0.71 NOTUM (0.39) CES2CES1TGM2ALDH1A1CA12
SCHEMBL17514862 0.69 EGLN2 (0.40) MEN1KMT2A
SCHEMBL17984227 0.69 CES2 (0.48) CES2CES1TGM2ALDH1A1CA12
SCHEMBL31711757 0.69 CA1 (0.33) CES2CES1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881811-B2 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20040147710-A1 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY LIMITED (JP) 2004-07-29 US disclosed