Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352434 | 1.00 | HTR6 (0.48) | HTR6CYP3A4CYP2D6CCR4FKBP1A | |
| SCHEMBL5361336 | 1.00 | HTR6 (0.48) | HTR6CYP3A4CYP2D6CCR4FKBP1A | |
| SCHEMBL5362401 | 1.00 | HTR6 (0.48) | HTR6CYP3A4CYP2D6CCR4FKBP1A | |
| SCHEMBL5352437 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5361339 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL6519764 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5362405 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5360618 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5355636 | 0.81 | PPARG (0.53) | HTR6PPARGPPARDPPARA | |
| SCHEMBL5350312 | 0.81 | PPARG (0.53) | HTR6PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1533299-A1 | INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | Meiji Dairies Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |