Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6519761 | 1.00 | HTR6 (0.48) | HTR6CYP3A4CYP2D6CCR4FKBP1A | |
| SCHEMBL5352434 | 1.00 | HTR6 (0.48) | HTR6CYP3A4CYP2D6CCR4FKBP1A | |
| SCHEMBL5361336 | 1.00 | HTR6 (0.48) | HTR6CYP3A4CYP2D6CCR4FKBP1A | |
| SCHEMBL5352437 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5361339 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL6519764 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5362405 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5360618 | 0.86 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5355636 | 0.81 | PPARG (0.53) | HTR6PPARGPPARDPPARA | |
| SCHEMBL5350312 | 0.81 | PPARG (0.53) | HTR6PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307098-B2 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20050261357-A1 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1533299-A1 | INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | Meiji Dairies Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261357-A1 | Indole derivatives and drugs containing the same | IDO1, TPH1, IDO2 | HTR6 26/4885CYP3A4 1996/4885CYP2D6 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.