Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352437 | 1.00 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5360618 | 1.00 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5362405 | 1.00 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5361339 | 1.00 | HTR6 (0.59) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5361336 | 0.86 | HTR6 (0.48) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL6519761 | 0.86 | HTR6 (0.48) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5360612 | 0.86 | HTR6 (0.48) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5352434 | 0.86 | HTR6 (0.48) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL5362401 | 0.86 | HTR6 (0.48) | HTR6CYP3A4CYP2D6PPARGPPARD | |
| SCHEMBL1519041 | 0.84 | HTR6 (0.72) | HTR6PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307098-B2 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| EP-1533299-A1 | INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | Meiji Dairies Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |