Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MLNR | O43193 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520146 | 1.00 | HTR2A (0.60) | HTR2AIDO1P2RX7LMNACYP2D6 | |
| SCHEMBL6520157 | 1.00 | HTR2A (0.60) | HTR2AIDO1P2RX7LMNACYP2D6 | |
| SCHEMBL22738383 | 0.96 | LMNA (0.58) | HTR2AIDO1P2RX7LMNACYP2D6 | |
| SCHEMBL14271387 | 0.88 | HTR2A (0.58) | HTR2AP2RX7LMNACYP2D6MEN1 | |
| SCHEMBL1152298 | 0.83 | P2RX7 (0.56) | HTR2AIDO1P2RX7LMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL11204771 | 0.83 | LMNA (0.58) | HTR2AP2RX7LMNACYP2D6MEN1 | |
| SCHEMBL9696448 | 0.83 | P2RX7 (0.48) | HTR2AP2RX7LMNACYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL11371006 | 0.82 | LMNA (0.57) | HTR2AP2RX7LMNACYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL11371000 | 0.82 | LMNA (0.57) | HTR2AP2RX7LMNACYP2D6MEN1 | |
| SCHEMBL431162 | 0.82 | HTR2A (0.68) | HTR2ALMNACYP2D6MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834555-B2 | Method for treating pain syndrome and other disorders | VM Therapeutics LLC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20160318930-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM THERAPEUTICS LLC (US) | 2016-11-03 | — | — | US | disclosed |
| US-9402848-B2 | Method for treating pain syndrome and other disorders | VM THERAPEUTICS LLC (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150150875-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM DISCOVERY, INC. | 2015-06-04 | — | — | US | disclosed |
| US-20140378476-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM DISCOVERY, INC. | 2014-12-25 | — | — | US | disclosed |
| US-8865727-B2 | Method for treating pain syndrome and other disorders | VM THERAPEUTICS LLC (US) | 2014-10-21 | — | — | US | disclosed |
| US-20110053960-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | VM DISCOVERY INC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378476-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | CACNA1G, CACNA1H, CACNA1A | HTR2A 606/4885IDO1 4379/4885P2RX7 199/4885 |
| US-20150150875-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | CACNA1G, CACNA1H, CACNA1A | HTR2A 606/4885IDO1 4379/4885P2RX7 199/4885 |
| US-20160318930-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | CACNA1G, CACNA1H, CACNA1A | HTR2A 606/4885IDO1 4379/4885P2RX7 199/4885 |
| US-20110053960-A1 | METHOD FOR TREATING PAIN SYNDROME AND OTHER DISORDERS | CACNA1G, CACNA1H, CACNA1A | HTR2A 606/4885IDO1 4379/4885P2RX7 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.