Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.61 |
| ▸ | SELP | P16109 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206313 | 0.90 | EPHX2 (0.66) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL20263717 | 0.89 | MAPT (0.56) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL19176854 | 0.85 | MCL1 (0.53) | FAAHSELPEPHX2CASP2NAAA | |
| SCHEMBL20263728 | 0.85 | MAPT (0.56) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL1117284 | 0.84 | FAAH (0.62) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL1880781 | 0.83 | FAAH (0.64) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL31206518 | 0.83 | CASP2 (0.62) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL25350370 | 0.82 | FAAH (0.77) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL11170358 | 0.82 | FAAH (0.77) | FAAHSELPDNM1EPHX2CASP2 | |
| SCHEMBL846255 | 0.82 | FAAH (0.77) | FAAHSELPDNM1EPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283143-B1 | PROCESS FOR PRODUCING SPHINGOLIPIDS BY N-ACYLATION OF LYSOSPHINGOLIPIDS EMPLOYING A FUNGAL LIPASE | EVONIK DEGUSSA GMBH (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-2283144-B1 | PROCESS FOR PRODUCING SPHINGOLIPIDS BY N-ACYLATION OF LYSOSPHINGOLIPIDS EMPLOYING A LIPASE AND A FATTY ACID GLYCEROL ESTER | EVONIK DEGUSSA GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| CN-102057049-B | Method for producing sphingolipids by enzymatic N-acylation of lysosphingolipids using fungal lipases and fatty acid alkyl esters | EVONIK GOLDSCHMIDT GMBH (DE) | 2014-10-01 | — | — | CN | disclosed |
| CN-102057050-B | Method for producing sphingolipids by enzymatic N-acylation of lysosphingolipids using a lipase and a fatty acid glycerol ester | EVONIK GOLDSCHMIDT GMBH | 2014-06-11 | — | — | CN | disclosed |
| US-20110065801-A1 | ENZYMATIC SYNTHESIS OF SPHINGOLIPIDS | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| EP-0649836-B1 | N-(long-chain acyl)amino nitrile and process for the preparation thereof | KAO CORP (JP) | 1998-02-25 | — | — | EP | disclosed |
| US-5646317-A | AMIDATION, HYDROLYSIS | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0649836-A1 | Processes for the preparation of N-(long-chain acyl)amino acid and salt thereof, and intermediate amidonitrile and process for the preparation thereof | Kao Corporation (JP) | 1995-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065801-A1 | ENZYMATIC SYNTHESIS OF SPHINGOLIPIDS | ASAH1, SMPD1, ASAH2 | FAAH 145/4885SELP 3912/4885DNM1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.