SCHEMBL6520684

SCHEMBL6520684

O=C(O)C(CO)OC(=O)C(CO)OP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
LAP3 P28838 2/20 0.34
PGD P52209 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4867885 0.88 PGK1 (0.44) PGK1PGK2LAP3PGD
SCHEMBL28012475 0.86 PGK1 (0.40) PGK1PGK2LAP3PGD
SCHEMBL77985 0.86 PGK1 (0.40) PGK1PGK2LAP3PGD
SCHEMBL2726719 0.86 PGK1 (0.40) PGK1PGK2LAP3PGD
SCHEMBL722606 0.78 CA4 (0.36)
Serine SCHEMBL8169130 0.76 LAP3 (0.44) LAP3
SCHEMBL2413262 0.74 FOLH1 (0.44) LAP3
SCHEMBL8139325 0.73 SMPD1 (0.36) PGK1PGK2LAP3PGD
SCHEMBL1758798 0.73 OR51E2 (0.40)
Water SCHEMBL30600042 0.72 FOLH1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050143472-A1 Novel treatment for pathologies associated with oxidative damage REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2005-06-30 US disclosed
WO-2003068167-A2 NOVEL TREATMENT FOR PATHOLOGIES ASSOCIATED WITH OXIDATIVE DAMAGE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-21 WO disclosed