Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL30600042 | 0.98 | FOLH1 (0.43) | FOLH1LMNA | |
| SCHEMBL29065856 | 0.84 | FOLH1 (0.60) | FOLH1LMNA | |
| Choline SCHEMBL30363206 | 0.82 | MEN1 (0.38) | FOLH1LMNA | |
| SCHEMBL77985 | 0.82 | PGK1 (0.40) | FOLH1SMPD1LAP3 | |
| SCHEMBL2726719 | 0.82 | PGK1 (0.40) | FOLH1SMPD1LAP3 | |
| SCHEMBL28012475 | 0.82 | PGK1 (0.40) | FOLH1SMPD1LAP3 | |
| SCHEMBL8139325 | 0.77 | SMPD1 (0.36) | SMPD1LAP3 | |
| SCHEMBL30990064 | 0.76 | SMPD1 (0.31) | SMPD1 | |
| SCHEMBL19583579 | 0.76 | SMPD1 (0.31) | SMPD1 | |
| SCHEMBL722606 | 0.74 | CA4 (0.36) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116200354-B | Phosphoglycerol oxidase mutant with improved thermal stability and application thereof | 西安文理学院 | 2024-12-13 | — | — | CN | disclosed |
| CN-117529307-A | Particles comprising amorphous divalent metal carbonate | 阿莫菲克公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114774381-B | Preparation method of phosphoglycerate oxidase | 陕西永磊生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114107061-A | Seawater microalgae culture medium | 宁波浮田生物技术有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-20130065257-A1 | ENZYME-LOGIC BIOSENSING | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2013-03-14 | — | — | US | disclosed |
| WO-2011116151-A2 | ENZYME-LOGIC BIOSENSING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-22 | — | — | WO | disclosed |
| US-4900730-A | USING CHELATING AGENT AND SOLVENT; HIGH OSMOTIC PRESSURE | TOYO JOZO CO., LTD. (JP) | 1990-02-13 | — | — | US | disclosed |