SCHEMBL6520813

SCHEMBL6520813

CC1C=CC(C)C2C(=O)OC(=O)C12

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
PPM1B O75688 1/20 0.39
LMNA P02545 1/20 0.39
PPP1CC P36873 1/20 0.39
TFPI2 P48307 1/20 0.39
RAB9A P51151 1/20 0.39
PPP5C P53041 1/20 0.39
PPP1CA P62136 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TP53 P04637 1/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39
POLB P06746 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821226 1.00 TDP1 (0.39) TDP1KDM4EGMNNPPM1BLMNA
SCHEMBL15672321 1.00 TDP1 (0.39) TDP1KDM4EGMNNPPM1BLMNA
SCHEMBL19604953 0.87 KDM4E (0.31) TDP1KDM4EGMNNPPM1BLMNA
SCHEMBL13694674 0.83
SCHEMBL21689115 0.83
SCHEMBL19067982 0.79 ALDH1A1 (0.36)
SCHEMBL597567 0.77 KDM4E (0.31) TDP1KDM4EGMNNPPM1BLMNA
SCHEMBL4352284 0.74 KMT2A (0.41) TDP1KDM4EGMNNPPM1BLMNA
SCHEMBL1739727 0.74 KMT2A (0.41) TDP1KDM4EGMNNPPM1BLMNA
SCHEMBL1473414 0.74 KMT2A (0.41) TDP1KDM4EGMNNPPM1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112714759-B Metal salt, crystallization nucleating agent composition, polyolefin resin composition, and polyolefin resin molded body 新日本理化株式会社 2023-12-12 CN disclosed
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 US disclosed
US-20230203239-A1 Cyclic ether-anhydride photopolyaddition and uses thereof UNIVERSITÉ DE HAUTE-ALSACE (FR) 2023-06-29 US disclosed
WO-2021191237-A1 CYCLIC ETHER-ANHYDRIDE PHOTOPOLYADDITION AND USES THEREOF UNIVERSITÉ DE HAUTE-ALSACE (FR) 2021-09-30 WO disclosed
EP-3786569-A1 HEAT TRANSFER SYSTEM COMPRISING BRAZED ALUMINUM, METHOD, HEAT TRANSFER FLUID, AND ADDITIVE PACKAGE Prestone Products Corporation (US) 2021-03-03 EP disclosed
US-9249348-B2 Heat transfer system additive package PRESTONE PRODUCTS CORPORATION (US) 2016-02-02 US disclosed
US-9249348-B2 Heat transfer system additive package PRESTONE PRODUCTS CORPORATION (US) 2016-02-02 US disclosed
US-20150140497-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, POLYMERIC COMPOUND, COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2015-05-21 US disclosed
US-20140225025-A1 HEAT TRANSFER SYSTEM ADDITIVE PACKAGE PRESTONE PRODUCTS CORPORATION (US) 2014-08-14 US disclosed
US-20140225025-A1 HEAT TRANSFER SYSTEM ADDITIVE PACKAGE PRESTONE PRODUCTS CORPORATION (US) 2014-08-14 US disclosed
EP-0411333-A1 Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-02-06 EP disclosed
US-4933420-A Epoxy resins containing phosphonium catalysts THE DOW CHEMICAL COMPANY (US) 1990-06-12 US disclosed
EP-0360195-A2 Epoxy resins containing phosphonium catalysts THE DOW CHEMICAL COMPANY (US) 1990-03-28 EP disclosed
EP-0302934-A1 ALICYCLIC DICARBOXYLIC ACID DERIVATIVES AND MUSCLE RELAXANTS CONTAINING THEM AS EFFECTIVE INGREDIENTS NIPPON ZEON CO., LTD. (JP) 1989-02-15 EP disclosed
EP-0109562-B1 SUCCINIMIDE DERIVATIVES AND THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP disclosed
EP-0209174-A2 Process for preparing advanced epoxy resin compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-01-21 EP disclosed
US-4634757-A REACTION OF POLYEPOXIDE WITH PHENOL, ACID OR ANHYDRIDE SHELL OIL COMPANY (US) 1987-01-06 US disclosed
US-4598078-A N-(substituted piperazinyl) alkylbicyclic succinimide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-07-01 US disclosed
EP-0109562-A1 Succinimide derivatives and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-30 EP disclosed
US-4398013-A HALOGENONIUM SALT GENERAL ELECTRIC COMPANY (US) 1983-08-09 US disclosed