SCHEMBL6521233

SCHEMBL6521233

Cc1ccc(C2[CH]CC(c3ccc(C)cc3)[CH]C2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
MAP1LC3B Q9GZQ8 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PRCP P42785 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8684748 0.97 ACHE (0.44) ACHETDP1MAPTHTR2AHTR2C
SCHEMBL4361553 0.80 ACHE (0.33) ACHETDP1MAPTHTR2AHTR2C
SCHEMBL6519587 0.72 TSHR (0.42) MAPTHTR2CCYP1A2CYP3A4CYP2C9
SCHEMBL148194 0.70 LMNA (0.44) MAPTHTR2AHTR2CHTR2BMAP1LC3B
SCHEMBL21433657 0.70 KDM1A (0.46) ACHETDP1HTR2AHTR2CHTR2B
SCHEMBL1669870 0.70 KDM1A (0.46) TDP1MAPTHTR2CHTR2BMEN1
SCHEMBL29097668 0.70 SLC18A3 (0.38) ACHETDP1MAPTHTR2AHTR2C
SCHEMBL17599623 0.70 HTR2A (0.44) ACHETDP1MAPTHTR2AHTR2C
SCHEMBL22436646 0.70 TSHR (0.44) ACHEMAPTMEN1KMT2AALDH1A1
SCHEMBL1779485 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487071-B2 Polyether polymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-16 US disclosed
US-20110065889-A1 POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed