Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154270 | 1.00 | TSHR (0.42) | TSHRALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL3690693 | 1.00 | TSHR (0.42) | TSHRALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL11312924 | 1.00 | TSHR (0.42) | TSHRALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL6521289 | 1.00 | TSHR (0.42) | TSHRALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL6413786 | 0.91 | NAAA (0.42) | TSHRLMNA | |
| SCHEMBL3362063 | 0.87 | MMP1 (0.43) | TSHRALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL6406010 | 0.85 | MMP1 (0.45) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL1153506 | 0.84 | TP53 (0.43) | TSHRALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL6406120 | 0.83 | L3MBTL1 (0.41) | TSHRALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL6406988 | 0.79 | NAAA (0.40) | ALDH1A1MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005348686-A | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL CO LTD | 2005-12-22 | — | — | JP | disclosed |
| US-4258207-A | Cyclopropanecarboxylate pesticides preparation | SHELL OIL COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4241081-A | Cyclopropanecarboxylate pesticides | SHELL OIL COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4209642-A | Cyclopropylmethanol pesticide | SHELL OIL COMPANY (US) | 1980-06-24 | — | — | US | disclosed |