Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.40 |
| ▸ | SMYD2 | Q9NRG4 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846730 | 0.97 | CHRM3 (0.44) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Trifluoroacetic Acid SCHEMBL6523373 | 0.96 | CHRM2 (0.42) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| SCHEMBL1245050 | 0.93 | CHRM2 (0.44) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Trifluoroacetic Acid SCHEMBL6527403 | 0.93 | CHRM3 (0.44) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Trifluoroacetic Acid SCHEMBL6521595 | 0.92 | CHRM3 (0.41) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Sulfuric Acid SCHEMBL1246196 | 0.91 | CHRM2 (0.44) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Trifluoroacetic Acid SCHEMBL6523294 | 0.91 | CHRM3 (0.43) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Trifluoroacetic Acid SCHEMBL6525352 | 0.91 | CHRM3 (0.44) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| Trifluoroacetic Acid SCHEMBL6522866 | 0.90 | SMYD2 (0.49) | CHRM3CHRM2ADRB2SMYD2DRD2 | |
| SCHEMBL12788933 | 0.89 | CHRM2 (0.44) | CHRM3CHRM2ADRB2SMYD2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476265-B2 | Compounds-801 | ASTRAZENECA AB (SE) | 2013-07-02 | — | — | US | disclosed |
| US-8455483-B2 | Compounds—801 | ASTRAZENECA AB (SE) | 2013-06-04 | — | — | US | disclosed |
| US-20130018037-A1 | Compounds - 801 | ASTRAZENECA UK LIMITED (GB) | 2013-01-17 | — | — | US | disclosed |
| US-20110053909-A1 | Compounds - 801 | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018037-A1 | Compounds - 801 | ADRA2C, ADRB2, ADRB1 | CHRM3 97/4885CHRM2 157/4885ADRB2 2/4885 |
| US-20110053909-A1 | Compounds - 801 | ADRA2C, ADRB2, ADRB1 | CHRM3 97/4885CHRM2 157/4885ADRB2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.