Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525258 | 0.90 | TLR4 (0.34) | TLR4TLR2OGAACHE | |
| SCHEMBL6522747 | 0.87 | OGA (0.35) | TLR4TLR2OGA | |
| SCHEMBL6519237 | 0.83 | TLR4 (0.39) | TLR4TLR2OGA | |
| SCHEMBL6522943 | 0.82 | OGA (0.35) | OGA | |
| SCHEMBL6520847 | 0.81 | OGA (0.35) | OGAACHEMAOAMAOB | |
| SCHEMBL1036429 | 0.81 | CYP3A4 (0.42) | TLR4TLR2OGA | |
| SCHEMBL6517979 | 0.80 | CYP2D6 (0.35) | OGAMAOAMAOB | |
| SCHEMBL6519327 | 0.80 | GPR55 (0.37) | TLR4TLR2OGAMAOAMAOB | |
| SCHEMBL6525257 | 0.79 | OGA (0.31) | OGA | |
| SCHEMBL6516955 | 0.78 | CYP3A4 (0.33) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053982-A1 | ETHER BENZYLIDENE PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053982-A1 | ETHER BENZYLIDENE PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | FAAH, FAAH2, CNR2 | TLR4 2819/4885TLR2 2211/4885OGA 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.