Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL3396777 | 0.85 | ALDH1A1 (0.53) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL375765 | 0.83 | RAB9A (0.53) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| Acetic Acid SCHEMBL6285526 | 0.81 | ALDH1A1 (0.53) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| Pyrrole SCHEMBL28308888 | 0.79 | RAB9A (0.46) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| Toluene SCHEMBL10939845 | 0.78 | MAPT (0.48) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| Acetonitrile SCHEMBL10666479 | 0.78 | ALDH1A1 (0.46) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL2520545 | 0.77 | RAB9A (0.47) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL1714515 | 0.77 | ALDH1A1 (0.53) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| 1-Methylimidazole SCHEMBL27776909 | 0.77 | ALDH1A1 (0.66) | CYP3A4NFKB1QPCTHSD17B10QPCTL | |
| SCHEMBL9680844 | 0.75 | MAOA (0.46) | CYP1A2ALDH1A1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050208199-A1 | Methods and compositions for synthesis of 3'-aminolinkers | U CHICAGO ARGONNE LLC | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050208199-A1 | Methods and compositions for synthesis of 3'-aminolinkers | MECP2, DNMT1, DNMT3L | CYP1A2 4428/4885CYP3A4 4086/4885CYP2D6 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.