Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6457039 | 1.00 | — | — | |
| Alcohol SCHEMBL28160593 | 1.00 | DNM1 (0.75) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Alcohol SCHEMBL11462091 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Decylamine SCHEMBL989202 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Alcohol SCHEMBL11466733 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Alcohol SCHEMBL11455986 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Pentadecylamine SCHEMBL11453009 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Alcohol SCHEMBL474302 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Hexadecylamine SCHEMBL3962485 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Alcohol SCHEMBL11471709 | 0.97 | DNM1 (0.81) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050173830-A1 | Moldings based on polyurethane binders | HENKEL AG & CO. KGAA (DE) | 2005-08-11 | — | — | US | disclosed |