SCHEMBL6523485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6525895	0.92	NPC1 (0.51)	NPC1PTPN1FNTAFNTBALDH1A1
	SCHEMBL6514918	0.89	NPC1 (0.45)	NPC1PTPN1FNTAFNTBALDH1A1
	SCHEMBL6518026	0.86	NPC1 (0.46)	NPC1PTPN1FNTAFNTBALDH1A1
	SCHEMBL6517349	0.85	NPC1 (0.48)	NPC1PTPN1FNTAFNTBALDH1A1
	SCHEMBL6520550	0.82	NPC1 (0.42)	NPC1PTPN1ALDH1A1KDM4EMAPT
	SCHEMBL6926548	0.80	PTPN1 (0.59)	NPC1PTPN1ALDH1A1KDM4EMAPT
	SCHEMBL6515547	0.78	KMT2A (0.48)	NPC1ALDH1A1KDM4EMAPTHPGD
	SCHEMBL6522603	0.77	KDM4E (0.51)	NPC1PTPN1ALDH1A1KDM4EMAPT
	SCHEMBL4828442	0.76	NPC1 (0.59)	NPC1PTPN1FNTAFNTBALDH1A1
	SCHEMBL8396440	0.76	PTPN1 (0.61)	NPC1PTPN1FNTAFNTBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.