Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26597083 | 0.85 | CNR2 (0.62) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL854153 | 0.85 | CDC25B (0.60) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5857951 | 0.85 | PTPN1 (0.71) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29457006 | 0.85 | PTPN1 (0.71) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8948846 | 0.83 | MTNR1A (0.46) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4707024 | 0.82 | PTPN1 (0.62) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8948915 | 0.82 | MTNR1A (0.45) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22534104 | 0.81 | POLB (0.50) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8396440 | 0.81 | PTPN1 (0.61) | PTPN1MAPTALDH1A1MEN1KMT2A | |
| Methoxymethane SCHEMBL29175314 | 0.81 | PTPN1 (0.61) | PTPN1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102516210-A | Preparation method of 2,3-dicyanofuran compound | UNIV EAST CHINA SCIENCE & TECH | 2012-06-27 | — | — | CN | claimed |
| CN-112755022-B | Application of 3-aryl pyrazolone compound in preparation of pancreatic lipase inhibitor | 浙江工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-112755022-A | Application of 3-aryl pyrazolone compound in preparation of pancreatic lipase inhibitor | 浙江工业大学 | 2021-05-07 | — | — | CN | disclosed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | disclosed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | disclosed |
| CN-102993166-B | Preparation method and application of 3H-1,2-dithiole-3-thioketone compound | UNIV SOOCHOW | 2015-05-13 | — | — | CN | disclosed |
| CN-102807557-B | 3H-1,2-dithio-cyclopentene-3-thioketone compound and application thereof | UNIV SOOCHOW | 2015-02-04 | — | — | CN | disclosed |
| CN-102993166-A | Preparation method and application of 3H-1,2-dithiole-3-thioketone compound | UNIV SOOCHOW | 2013-03-27 | — | — | CN | disclosed |
| CN-102807557-A | 3H-1,2-dithio-cyclopentene-3-thioketone compound and application thereof | UNIV SOOCHOW | 2012-12-05 | — | — | CN | disclosed |
| CN-102516210-A | Preparation method of 2,3-dicyanofuran compound | UNIV EAST CHINA SCIENCE & TECH | 2012-06-27 | — | — | CN | disclosed |
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |
| US-6518429-B2 | Anticancer agents, treating restenosis, atherosclerosis and hepatitis virus | LG CHEMICAL, LTD. (KR) | 2003-02-11 | — | — | US | disclosed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |
| US-20020137769-A1 | Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof | LG CHEMICAL LTD. | 2002-09-26 | — | — | US | disclosed |
| US-6268363-B1 | ANTITUMOR | LG CHEMICAL LTD. (KR) | 2001-07-31 | — | — | US | disclosed |
| EP-1045846-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028315-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1999-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | TXN2, TXN, TXNRD2 | PTPN1 1945/4885MAPT 3443/4885ALDH1A1 370/4885 |
| US-20020137769-A1 | Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof | FNTA, FNTB, FDPS | PTPN1 3281/4885MAPT 2463/4885ALDH1A1 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.