Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410286 | 0.84 | CHRNB2 (0.41) | SPR | |
| SCHEMBL28408901 | 0.82 | RIPK1 (0.35) | SPRRIPK1 | |
| SCHEMBL3310289 | 0.81 | GRM2 (0.32) | — | |
| SCHEMBL23866581 | 0.80 | CHRNB2 (0.46) | — | |
| SCHEMBL21661510 | 0.80 | CHRNB2 (0.46) | — | |
| SCHEMBL21661355 | 0.80 | CHRNB2 (0.46) | — | |
| SCHEMBL19815798 | 0.80 | GABRR1 (0.36) | — | |
| SCHEMBL1907444 | 0.75 | — | — | |
| SCHEMBL20498553 | 0.75 | DPP4 (0.33) | — | |
| SCHEMBL22191115 | 0.75 | DPP4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618103-B2 | Inhibitors of JAK | HOFFMANN-LA ROCHE INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20110059118-A1 | INHIBITORS OF JAK | DE VICENTE FIDALGO JAVIER | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059118-A1 | INHIBITORS OF JAK | JAK1, JAK3, JAK2 | SPR 3853/4885RIPK1 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.