Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 6/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6524323 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM4PARP1STAT3 | |
| SCHEMBL6520781 | 0.91 | ADRB2 (0.41) | CHRM4PARP1STAT3MDM2RORC | |
| SCHEMBL3711560 | 0.91 | PARP1 (0.41) | CHRM4PARP1STAT3P2RX7KDM1A | |
| SCHEMBL12788268 | 0.89 | CHRM4 (0.43) | CHRM2CHRM4PARP1STAT3P2RX7 | |
| SCHEMBL6519504 | 0.89 | PARP1 (0.45) | CHRM4PARP1STAT3SCN9AADRB2 | |
| SCHEMBL6519844 | 0.88 | ALOX5AP (0.42) | PARP1STAT3MDM2ADRB2 | |
| SCHEMBL6517503 | 0.88 | ALOX5AP (0.42) | PARP1STAT3MDM2ADRB2 | |
| SCHEMBL3659359 | 0.87 | STAT3 (0.43) | PARP1STAT3ADRB2 | |
| SCHEMBL3659855 | 0.87 | STAT3 (0.45) | STAT3ADRB2 | |
| SCHEMBL6520829 | 0.86 | STAT3 (0.42) | PARP1STAT3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059942-A1 | Azetidinyl G-Protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059942-A1 | Azetidinyl G-Protein Coupled Receptor Agonists | GPR119, GIPR, GPR39 | CHRM2 473/4885CHRM1 534/4885CHRM4 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.