Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522432 | 0.86 | HMOX1 (0.39) | ACACBHMOX1HSP90AA1LNPEPNAMPT | |
| SCHEMBL6523540 | 0.86 | HMOX1 (0.39) | ACACBHMOX1HSP90AA1LNPEPNAMPT | |
| SCHEMBL6522478 | 0.86 | HMOX1 (0.50) | ACACBHMOX1HSP90AA1LNPEPNAMPT | |
| SCHEMBL6522916 | 0.85 | LNPEP (0.37) | ACACBLNPEPNAMPT | |
| SCHEMBL6523694 | 0.85 | LIPE (0.43) | ACACBHMOX1DPP4DPP7 | |
| SCHEMBL6523359 | 0.85 | HMOX1 (0.38) | ACACBHMOX1LNPEPSMYD3NAMPT | |
| SCHEMBL6518379 | 0.84 | HMOX1 (0.43) | ACACBHMOX1DPP4DPP7NAMPT | |
| Hydrochloric Acid SCHEMBL6524534 | 0.81 | ACACB (0.43) | ACACBHMOX1DPP4DPP7HSP90AA1 | |
| SCHEMBL6522911 | 0.80 | DPP4 (0.41) | HMOX1DPP4DPP7LNPEPNAMPT | |
| SCHEMBL6522055 | 0.80 | DPP4 (0.41) | HMOX1DPP4DPP7LNPEPNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | F12, F2, C3AR1 | ACACB 3542/4885HMOX1 334/4885DPP4 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.