Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782321 | 0.84 | NPBWR1 (0.40) | KIF11NPBWR1ADAMTS5KDM4EMETAP2 | |
| SCHEMBL16168464 | 0.84 | NPBWR1 (0.40) | KIF11NPBWR1ADAMTS5KDM4EMETAP2 | |
| SCHEMBL5679579 | 0.78 | MAPT (0.57) | KIF11NPBWR1KDM4EMETAP2SCN10A | |
| SCHEMBL5681855 | 0.76 | NPSR1 (0.59) | KIF11NPBWR1KDM4EMETAP2DGAT1 | |
| SCHEMBL10284433 | 0.75 | KIF11 (0.47) | KIF11NPBWR1KDM4EMETAP2SCN10A | |
| SCHEMBL18628731 | 0.75 | NPBWR1 (0.43) | KIF11NPBWR1KDM4EMETAP2SCN10A | |
| SCHEMBL2360716 | 0.75 | MASP2 (0.48) | KIF11NPBWR1KDM4EMETAP2SCN10A | |
| SCHEMBL21496795 | 0.75 | NPBWR1 (0.43) | KIF11NPBWR1KDM4EMETAP2SCN10A | |
| SCHEMBL666767 | 0.75 | NPBWR1 (0.43) | KIF11NPBWR1KDM4EMETAP2DGAT1 | |
| SCHEMBL2711960 | 0.75 | KDM4E (0.50) | KIF11NPBWR1KDM4EMETAP2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |