Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.49 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792217 | 1.00 | NAAA (0.58) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL12791709 | 1.00 | NAAA (0.58) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL12791923 | 1.00 | NAAA (0.58) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL12792093 | 1.00 | NAAA (0.58) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL12792190 | 1.00 | NAAA (0.58) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL9290503 | 0.98 | NAAA (0.57) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL25607772 | 0.98 | NAAA (0.57) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL9285558 | 0.97 | NAAA (0.55) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL25605083 | 0.97 | NAAA (0.55) | NAAACASP2DNM1PAOXFAAH | |
| SCHEMBL9290065 | 0.97 | NAAA (0.62) | NAAACASP2DNM1PAOXFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174459-A1 | LIPID CONTAINING FORMULATIONS | ARBUTUS BIOPHARMA CORPORATION (US) | 2023-06-08 | — | — | US | disclosed |
| US-11420931-B2 | Lipid containing formulations | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-08-23 | — | — | US | disclosed |
| US-20200361854-A1 | LIPID CONTAINING FORMULATIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-11-19 | — | — | US | disclosed |
| US-20180065918-A1 | LIPID CONTAINING FORMULATIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2018-03-08 | — | — | US | disclosed |
| US-9663449-B2 | — | — | 2017-05-30 | — | — | US | disclosed |
| EP-2695608-B1 | Lipid containing formulations | ARBUTUS BIOPHARMA CORP (CA) | 2016-11-23 | — | — | EP | disclosed |
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140121393-A1 | LIPID CONTAINING FORMULATIONS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2014-05-01 | — | — | US | disclosed |
| EP-2695608-A2 | Lipid containing formulations | Tekmira Pharmaceuticals Corporation (CA) | 2014-02-12 | — | — | EP | disclosed |
| US-8642076-B2 | Lipid containing formulations | TEKMIRA PHARMACEUTICALS CORPORATION | 2014-02-04 | — | — | US | disclosed |
| EP-2068886-B1 | LIPID CONTAINING FORMULATIONS | TEKMIRA PHARMACEUTICALS CORP (CA) | 2013-09-18 | — | — | EP | disclosed |
| US-20120046478-A1 | LIPID CONTAINING FORMULATIONS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-02-23 | — | — | US | disclosed |
| US-8034376-B2 | Lipid containing formulations | Alnylam Pharamaceticals, Inc. (US) | 2011-10-11 | — | — | US | disclosed |
| US-20110052673-A1 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. | 2011-03-03 | — | — | US | disclosed |
| US-20110009641-A1 | Amine-containing lipids and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
| US-20090023673-A1 | LIPID CONTAINING FORMULATIONS | BANK OF AMERICA, N.A. | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361854-A1 | LIPID CONTAINING FORMULATIONS | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20180065918-A1 | LIPID CONTAINING FORMULATIONS | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20110052673-A1 | THERAPEUTIC COMPOSITIONS | PHOSPHO1, SGMS1, APOB | NAAA 625/4885CASP2 1497/4885DNM1 1206/4885 |
| US-20230174459-A1 | LIPID CONTAINING FORMULATIONS | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20140121393-A1 | LIPID CONTAINING FORMULATIONS | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20110009641-A1 | Amine-containing lipids and uses thereof | PHOSPHO1, CHMP4B, SGMS1 | NAAA 78/4885CASP2 3638/4885DNM1 946/4885 |
| US-11420931-B2 | Lipid containing formulations | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20090023673-A1 | LIPID CONTAINING FORMULATIONS | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20120046478-A1 | LIPID CONTAINING FORMULATIONS | LIPA, POLRMT, PHOSPHO1 | NAAA 1445/4885CASP2 3881/4885DNM1 528/4885 |
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | PHOSPHO1, CHMP4B, SGMS1 | NAAA 78/4885CASP2 3638/4885DNM1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.