SCHEMBL6525047

SCHEMBL6525047

CSc1ccc(NC(=O)Nc2cc(F)ccc2CN2C(=O)N(c3ccc(F)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.55
AR P10275 10/20 0.52
IGF1R P08069 3/20 0.40
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12584789 0.93 CNR1 (0.56) CNR1ARPGR
SCHEMBL8002084 0.91 CNR1 (0.58) CNR1ARPGR
SCHEMBL6526678 0.91 AR (0.51) CNR1ARPGR
SCHEMBL1974598 0.91 CNR1 (0.55) CNR1ARPGR
Hydrochloric Acid SCHEMBL6522010 0.91 CNR1 (0.57) CNR1ARPGR
SCHEMBL1971931 0.89 CNR1 (0.58) CNR1ARIGF1RPGR
SCHEMBL6522070 0.89 CNR1 (0.56) CNR1AR
SCHEMBL1975636 0.89 CNR1 (0.54) CNR1ARPGR
SCHEMBL1977359 0.89 CNR1 (0.61) CNR1ARIGF1RPGR
SCHEMBL6524574 0.89 CNR1 (0.61) CNR1ARIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110053947-A1 Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof SANOFI-AVENTIS (FR) 2011-03-03 US disclosed
US-20110053947-A1 Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof SANOFI-AVENTIS (FR) 2011-03-03 US disclosed
US-20110053947-A1 Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof SANOFI-AVENTIS (FR) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053947-A1 Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof PGC, LIPC, CEL CNR1 277/4885AR 1971/4885IGF1R 739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.