Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL29113729 | 0.89 | TSHR (0.39) | TSHRADRA2AADRA2BADRA2CCYP3A4 | |
| Fluorene SCHEMBL2550156 | 0.78 | MAPT (0.48) | TSHRMAPTCYP3A4MAOAADRA1D | |
| Naphthalene SCHEMBL8370666 | 0.75 | CYP3A4 (0.43) | TSHRMAPTCYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL451157 | 0.74 | TSHR (0.86) | TSHRMAPTCYP2A6MAOAMAOB | |
| SCHEMBL3057782 | 0.74 | TSHR (0.86) | TSHRMAPTCYP2A6MAOAMAOB | |
| SCHEMBL9662 | 0.74 | — | — | |
| SCHEMBL29354295 | 0.74 | — | — | |
| SCHEMBL8994760 | 0.73 | TSHR (0.48) | TSHRSIGMAR1CYP2A6MAOAMAOB | |
| Ether SCHEMBL7121208 | 0.73 | TSHR (0.57) | TSHRMAPTCYP3A4CYP2A6MAOA | |
| Biphenyl SCHEMBL277758 | 0.73 | ALDH1A1 (0.45) | TSHRMAPTCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069384-A1 | Preparation of polyindanebisphenols and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. | 2003-04-10 | — | — | US | claimed |
| EP-1056699-A1 | PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM | Alliedsignal, Inc. (US) | 2000-12-06 | — | — | EP | claimed |
| WO-1999043638-A1 | PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM | ALLIEDSIGNAL INC. (US) | 1999-09-02 | — | — | WO | claimed |
| US-6858304-B2 | Preparation of polyindanebisphenols and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030069384-A1 | Preparation of polyindanebisphenols and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. | 2003-04-10 | — | — | US | disclosed |
| US-6509063-B1 | Copolymerization with such as epoxy resin, epoxy function-alized elastomer or amorphous polycarbonate; impregnating monomer solution on fibrous support and desolvating to form dry laminate | HONEYWELL INTERNATIONAL INC. | 2003-01-21 | — | — | US | disclosed |
| EP-1056699-A1 | PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM | Alliedsignal, Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| US-6153721-A | CRACKING BISPHENOL A TO PRODUCE A MIXTURE COMPRISING P-ISOPROPENYLPHENOL AND PHENOL, COPOLYMERIZING THE RESULTING MIXTURE WITH AN ISOPROPENYLBENZENE COMPOUND IN A SUITABLE POLYMERIZATION MEDIUM TO YIELD A POLYINDANEBISPHENOL. | HONEYWELL INTERNATIONAL INC. (US) | 2000-11-28 | — | — | US | disclosed |
| WO-1999043638-A1 | PREPARATION OF POLYINDANEBISPHENOLS AND POLYMERS DERIVED THEREFROM | ALLIEDSIGNAL INC. (US) | 1999-09-02 | — | — | WO | disclosed |