SCHEMBL8994760

SCHEMBL8994760

C=CCCC.C=CCCC.c1ccc2c(c1)CCC2

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
SIGMAR1 Q99720 3/20 0.40
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
HTR1A P08908 2/20 0.37
CYP2A6 P11509 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
DRD4 P21917 1/20 0.35
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14917364 0.85 TSHR (0.52) TSHRSIGMAR1ALDH1A1KMT2AMEN1
Butane SCHEMBL2150151 0.80 TSHR (0.63) TSHRSIGMAR1ALDH1A1KMT2AMEN1
Butane SCHEMBL8909318 0.75 TSHR (0.72) TSHRSIGMAR1ALDH1A1KMT2AMEN1
Octane SCHEMBL4861483 0.74 TSHR (0.55) TSHRSIGMAR1ALDH1A1KMT2AMEN1
Propylamine SCHEMBL6559405 0.74 TSHR (0.55) TSHRSIGMAR1ALDH1A1KMT2AMEN1
SCHEMBL6525818 0.73 TSHR (0.48) TSHRSIGMAR1ALDH1A1CYP2A6MAOA
Alcohol SCHEMBL1872106 0.73 TSHR (0.60) TSHRALDH1A1KMT2AMEN1CYP2A6
Cycloheptane SCHEMBL28134106 0.72 TSHR (0.80) TSHRALDH1A1
Benzene SCHEMBL5685386 0.72 TSHR (0.80) TSHRALDH1A1
SCHEMBL451157 0.72 TSHR (0.86) TSHRCYP2A6MAOAMAOBDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5481053-A DIMERIZING ALPHA-METHYLSTYRENE USING ACTIVATED CLAY OR ACID CLAY AS CATALYST IN PRESENCE OF DI-LOWER-ALKYL CARBONATE OR ALKYLENE CARBONATE MITSUBISHI CHEMICAL CORPORATION (JP) 1996-01-02 US disclosed