SCHEMBL652590

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL654788	0.94	HRH4 (0.51)	HRH4HRH3CHEK2MAPTPARP1
	SCHEMBL654678	0.88	HRH4 (0.47)	HRH4HRH3CHEK2PARP1TNKS
	SCHEMBL653903	0.85	HSP90AA1 (0.51)	HRH4MEN1KMT2A
	SCHEMBL651846	0.83	HRH4 (0.64)	HRH4HRH3PARP1
	SCHEMBL653407	0.83	HRH4 (0.52)	HRH4HRH3MAPTPARP1MEN1
	SCHEMBL655731	0.81	PI4KB (0.59)	SMN1; SMN2MAPTMEN1KMT2AALDH1A1
	SCHEMBL654247	0.80	HRH4 (0.48)	HRH4HRH3SMN1; SMN2CHEK2MAPT
	SCHEMBL654404	0.79	HRH4 (0.59)	HRH4HRH3PARP1
	SCHEMBL654042	0.78	PI4KB (0.56)	HRH4SMN1; SMN2MAPTMEN1KMT2A
	SCHEMBL652090	0.78	HRH4 (0.47)	HRH4HRH3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.