SCHEMBL6525934

SCHEMBL6525934

C[SiH](C)[Hf](Cl)(Cl)(NC(C)(C)C)C1C=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648424 0.81
SCHEMBL5853277 0.80
SCHEMBL5854282 0.79 SIGMAR1 (0.31)
SCHEMBL5854290 0.78
SCHEMBL7647051 0.78 SIGMAR1 (0.33)
SCHEMBL6836597 0.77 BCHE (0.31)
SCHEMBL216950 0.77 HTR6 (0.33)
SCHEMBL6831461 0.76 ABCG2 (0.34)
SCHEMBL5853612 0.76 SIGMAR1 (0.32)
SCHEMBL6860294 0.76 TACR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881232-B1 Catalyst for olefin polymerization and process for the production of an olefin polymer TOSOH CORP (JP) 2005-03-16 EP disclosed
EP-0849292-B1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORP (JP) 2002-08-21 EP disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
US-6034187-A Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 2000-03-07 US disclosed
EP-0881232-A1 Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 1998-12-02 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed