SCHEMBL216950

SCHEMBL216950

C[SiH](C)[Hf](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.32
SIGMAR1 Q99720 2/20 0.31
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916191 0.88
SCHEMBL216943 0.83 SIGMAR1 (0.31) SIGMAR1
SCHEMBL6720596 0.82
SCHEMBL6469811 0.81 HTR2A (0.33) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL814607 0.80 HTR2A (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL8844481 0.80 CA12 (0.30)
SCHEMBL7106720 0.80
SCHEMBL3383168 0.79 HTR2A (0.35) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL217386 0.79 HTR6 (0.31) HTR6HTR2A
SCHEMBL6732154 0.79 HTR6 (0.33) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023562-B Production process of poly alpha-olefin 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-116023534-B Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2025-03-21 CN claimed
EP-3487924-B1 ROTOMOLDED COMPOSITIONS, ARTICLES, AND PROCESSES FOR MAKING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-06-12 EP claimed
CN-116023562-A Production process of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-116023534-A Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
US-10995203-B2 Rotomolded compositions, articles, and processes for making the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-05-04 US claimed
US-10676547-B2 Aluminum alkyls with pendant olefins on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-09 US claimed
US-20190284376-A1 Rotomolded Compositions, Articles, and Processes for Making the Same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-19 US claimed
US-20180201700-A1 Aluminum Alkyls with Pendant Olefins on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2018-07-19 US claimed
EP-3344385-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS ExxonMobil Chemical Patents Inc. (US) 2018-07-11 EP claimed
EP-1539841-A1 POLYMER PRODUCTION AT SUPERCRITICAL CONDITIONS ExxonMobil Chemical Patents, Inc. a Corporation of the State of Delaware (US) 2005-06-15 EP claimed
US-20040220359-A1 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-04 US claimed
WO-2004079456-A1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEM, LTD. (KR) 2004-09-16 WO claimed
US-20040138392-A1 polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-15 US claimed
US-20040127654-A1 Polymer production at supercritical conditions EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-01 US claimed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO claimed
WO-2004026921-A1 POLYMER PRODUCTION AT SUPERCRITICAL CONDITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-04-01 WO claimed
US-5708090-A Process for the preparation of a polypropylene molding composition HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-13 US claimed
US-5322902-A Process for the preparation of a polypropylene molding composition HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-21 US claimed
US-5280074-A Process for the preparation of a polypropylene molding composition HOECHST AG (DE) 1994-01-18 US claimed