Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL6528735 | 0.83 | ALDH1A1 (0.47) | KIF11THRACA12CA1CA2 | |
| SCHEMBL1403322 | 0.82 | LMNA (0.52) | THRACA12CA7CA9PTPRB | |
| SCHEMBL1403060 | 0.82 | LMNA (0.52) | THRACA12CA7CA9PTPRB | |
| SCHEMBL13771643 | 0.73 | CA1 (0.50) | KIF11THRACA12CA1CA2 | |
| SCHEMBL3194704 | 0.72 | HDAC1 (0.62) | MAPT | |
| SCHEMBL1797542 | 0.72 | L3MBTL1 (0.67) | L3MBTL1HPGD | |
| SCHEMBL3186279 | 0.72 | HDAC1 (0.74) | MAPTHPGD | |
| SCHEMBL1403154 | 0.71 | ALDH1A1 (0.55) | THRAHPGD | |
| SCHEMBL6752171 | 0.71 | CA1 (0.50) | KIF11CA12CA1CA2CA4 | |
| SCHEMBL18423665 | 0.70 | LMNA (0.47) | MAPTCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565432-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046094-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2004-06-03 | — | — | WO | disclosed |