Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744198 | 0.77 | TP53 (0.43) | ALDH1A1TP53SLC7A5 | |
| SCHEMBL6526330 | 0.74 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL13817462 | 0.69 | — | — | |
| Lactic Acid SCHEMBL27789980 | 0.67 | TP53 (0.79) | TP53SLC7A5ACHE | |
| Lactic Acid SCHEMBL3647672 | 0.67 | TP53 (0.79) | TP53SLC7A5ACHE | |
| Carbamic Acid SCHEMBL29148156 | 0.66 | ACHE (0.58) | ALDH1A1TP53SLC7A5ACHE | |
| SCHEMBL27980971 | 0.66 | — | — | |
| Alanine SCHEMBL28536204 | 0.65 | TP53 (0.36) | TP53SLC7A5 | |
| Carbamic Acid SCHEMBL28375472 | 0.65 | ACHE (0.47) | TP53SLC7A5ACHE | |
| Lactic Acid SCHEMBL5749785 | 0.65 | TP53 (0.73) | TP53SLC7A5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270847-A1 | NOVEL CARBAMATE AMINO ACID AND PEPTIDE PRODRUGS OF OPIATES AND USES THEREOF | SHIRE LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20110015182-A1 | NOVEL CARBAMATE AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | SHIRE LLC | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015182-A1 | NOVEL CARBAMATE AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | OPRL1, OPRM1, DNPEP | ALDH1A1 2705/4885TP53 3970/4885SLC7A5 41/4885 |
| US-20120270847-A1 | NOVEL CARBAMATE AMINO ACID AND PEPTIDE PRODRUGS OF OPIATES AND USES THEREOF | OPRL1, OPRM1, DNPEP | ALDH1A1 2945/4885TP53 4169/4885SLC7A5 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.