Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23510106 | 0.94 | GPR35 (0.56) | GPR35GAAALDH1A1HDAC3HDAC4 | |
| SCHEMBL23509888 | 0.88 | GPR35 (0.59) | GPR35GAAALDH1A1HDAC3HDAC4 | |
| SCHEMBL17086893 | 0.83 | GPR35 (0.48) | GPR35ALDH1A1HDAC1HSD17B3HTT | |
| SCHEMBL15274423 | 0.82 | GPR35 (0.46) | GPR35GAAALDH1A1GLAHSD17B3 | |
| SCHEMBL12617662 | 0.81 | GPR35 (0.62) | GPR35GAAALDH1A1HDAC3HDAC4 | |
| SCHEMBL17086928 | 0.79 | GPR35 (0.44) | GPR35ALDH1A1GLAHSD17B3HTT | |
| SCHEMBL15274424 | 0.79 | ALDH1A1 (0.49) | GPR35GAAALDH1A1HDAC3HDAC4 | |
| SCHEMBL6999984 | 0.79 | GPR35 (0.41) | GPR35ALDH1A1GLAHSD17B3HTT | |
| SCHEMBL14668342 | 0.78 | GPR35 (0.59) | GPR35GAAALDH1A1HDAC3HDAC4 | |
| SCHEMBL17426170 | 0.78 | HTT (0.44) | ALDH1A1HSD17B3HTTFFAR1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257601-B1 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-9716240-B2 | High molecular extinction coefficient metal dyes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-25 | — | — | US | disclosed |
| US-20110062541-A1 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | Changchun Applied Chemistry Institute of Chinese Academy of Sciences (CN) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110062541-A1 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | ANXA5, TRPM5, EPCAM | GPR35 3041/4885GAA 2433/4885ALDH1A1 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.